With Christian McCaffrey already on the injured reserve, Deebo Samuel has been ruled out due to injury for Week 3 in Los Angeles. Along with McCaffrey and Samuel, the 49ers could also be missing tight end George Kittle due to a hamstring injury.

The Los Angeles Rams’ injury issues haven’t just been on offense and defense. They’ve now bled into the special teams unit. Sean McVay said Friday before practice that kicker Joshua Karty is one of three players listed as questionable for Sunday’s game against the 49ers.

Tight end George Kittle and cornerback Charvarius Ward were surprise no-shows at Thursday’s practice, sidelined by leg injuries that suddenly put their availability in question for the 49ers’ game Sunday at the Los Angeles Rams.

After spending six seasons in red and gold, the former 49ers quarterback will be on the opposing sideline on Sunday in Los Angeles.

San Francisco 49ers left tackle Trent Williams found a possible silver lining in all the injuries the team is dealing with heading into Week 3.

The San Francisco 49ers will face the Los Angeles Rams on Sunday without wide receiver Deebo Samuel and running back Christian McCaffrey. Samuel sustained a calf strain in Sunday's game against the Minnesota Vikings,

The Los Angeles Rams are currently 0-2 heading into their Week 3 game against the San Francisco 49ers. They haven't had the best injury luck through two games with countless starters getting nicked up.